Colgate® Plax Alcohol Free Mouthwash
Non-alcohol Cetylpyridinium Chloride formula providing 12 hour protection against bacteria and plaque
Water, Glycerin, Propylene Glycol, Sorbitol, Poloxamer 407, Flavor, Cetylpyridinium Chloride, Potassium Sorbate, Sodium Fluoride, Sodium Saccharine, Menthol, CI 42051.
Mode of Action
Colgate® Plax Alcohol Free Mouthwash contains 0.075% Cetylpyridinium Chloride (CPC), which provides clinically proven 12 hour protection against bacteria and plaque.
Proof of Efficacy
- Fights plaque and bacteria for up to 12 hours1
- Kills 99% of bacteria on contact2
- A pre-procedural rinse that helps significantly reduce the number of aerosolized bacteria
- Helps reduce plaque and gum problems3,4,5
1. Data on file. Colgate-Palmolive Company. May 2013.
2. Data on file. Colgate-Palmolive Company. May 2013. Results improved with continued twice-daily use.
3. Data on file. Colgate-Palmolive Company. December 2012.
4. Data on file. Colgate-Palmolive Company. December 2012.
5. Data on file. Colgate-Palmolive Company. June 2013.
A clinical study to assess the 12-hour antimicrobial effects of cetylpyridinium chloride mouthwashes on supragingival plaque bacteria
He S, Wei Y, Fan X, Hu D, Sreenivasan PK.
Results: Subjects rinsing with the CPC-containing mouthwash realized a statistically significant (p<0.05) reduction in numbers of supragingival anaerobic bacteria at the 12-hour evaluation after a single use. In comparison to the control mouthwash, use of the CPC mouthwash in an alcohol base resulted in a 35.3% reduction in numbers of anaerobic plaque bacteria, while the CPC mouthwash in an alcohol-free base demonstrated a 34.5% reduction. Further, the analysis after twice-daily use for 14 days indicated that the CPC mouthwash in an alcohol base demonstrated a 73.8% reduction in anaerobic plaque bacteria, while the CPC mouthwash in an alcohol-free base demonstrated a 70.9% reduction in anaerobic plaque bacteria versus the control mouthwash.
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